A recent in-vivo study done by the UERM Memorial Medical Center Research team shows Difflam-C®, a locally-available antiseptic gargle solution, significantly alleviates the so-called COVID-19 Sore Throat – the most common symptom and tell-tale sign of people diagnosed with COVID-19.

The in-vivo study focused on establishing whether the combination of Benzydamine HCl and Chlorhexidine gluconate in Difflam-C® are effective in a real-world setting and was conducted on 219 COVID-19 patients from November 2021 until February 2022. This combination of active ingredients found in Difflam-C® solution have been gaining popularity in the Philippines particularly among doctors and healthcare professionals, with the synergistic action of its anti-inflammatory, analgesic, anesthetic, and antiseptic properties in relieving sore throat, as well as other symptoms of throat and mouth infection.

Clinically-tested Efficacy in COVID-19 Patients

Dr. Jennifer Nailes, MD 9 (leftmost), and Dr. Roberto Salvino, MD, the doctors who spearheaded the recent study done to evaluate the effectivity of the Difflam-C gargle against COVID 19-related throat pain were at a media roundtable held recently in Makati City, to reveal their findings. iNova Pharma Philippines Inc. are the makers of the Difflam-C gargle.

Lead investigators of the study have found that Difflam-C® significantly relieves the COVID-19 patients’ sore throat and alleviated throat discomfort associated with difficulty and/or pain in swallowing. Results also show that it helps shorten the duration of the said condition of COVID-19 patients, with the VAS scores of participants significantly decreased during course of treatment with Difflam-C®. “At specified time intervals, median VAS scores showed a decreasing trend from baseline until after 12 hours of Day 1 and is significantly different from baseline values . There were some participants whose sore throat pain were relieved within 30 minutes of first use of the solution which persisted even until after 12 hours,” said lead investigator Dr. Jennifer M. Nailes, MD, MSPH, Vice-President for Research of the University of the East Ramon Magsaysay Memorial Medical Center, Inc.

Gargle Against COVID-19 Sore Throat

Representatives from iNova Pharma Philippines Inc. (makers of Difflam-C gargle) together with Dr. Jennifer Nailes, MD, and Dr. Roberto Salvino, MD, the doctors who spearheaded the recent study on the effectivity of the Difflam-C gargle against COVID 19-related throat pain, recently held a media roundtable to reveal their study’s findings. Standing from left are:  Michelle dela Cruz, Marketing Manager of iNova Pharma Philippines Inc., Ria Enriquez, Difflam Product Manager; Dr. Jennifer Nailes, vice president for research at University of the East Ramon Magsaysay Memorial Medical Center Inc, Dr. Roberto Salvino, Medical Director, iNova Pharma Philippines Inc., and Eric Yuson, Associate Medical Affairs Manager of iNova.

“There was a noticeable shortening of the course of the sore throat in the study subjects, with their use of Difflam-C® during treatment. This gargle solution could be viewed as an effective treatment for patients with odynophagia (painful swallowing) or dysphagia (difficulty swallowing), conditions associated with severe sore throat among COVID-19 patients,” said Dr. Nailes.

Though yet to be published by Acta Medica Philippina, a peer-reviewed general medical and health science journal, these results are extremely encouraging and present a positive step in addressing the COVID-19 sore throat, using a widely available medicated gargle solution such as Difflam-C® in the study.

As cases rise and new Omicron variants are discovered, the results of this study could be valuable information in making the public more aware of clinically tested remedies to help address key symptoms like the COVID-19 sore throat. While Benzydamine HCl + Chlorhexidine gluconate (Difflam-C®) could be an effective treatment for COVID-19 sore throat, getting vaccinated with boosters, the observance of standard health protocols, and maintaining a healthy lifestyle are the current mainstays for the prevention of COVID-19 infection.

 

Amidst the pandemic, there is another disease that has gone under the radar and is silently affecting millions of people—Diabetes. Described as a chronic, noncommunicable disease, diabetes is a major public health problem globally and persons afflicted with it are also vulnerable to a host of other diseases such as hypertension, chronic kidney disease, and COVID.

“Last year, there were 463 million adults living with diabetes globally. That’s 1 out of 11 people who have the condition,” said Sanofi Philippines Country Lead, Amal Makhloufi Benchouk.

More alarmingly, the International Diabetes Federation (IDF) reports that a further 232 million people remain undiagnosed, with the majority of them believed to have type 2 diabetes. In the Philippines alone diabetes is one of the leading causes of death and places a heavy burden for many families who are living with disease.

“There are about 3.7 million diabetic Filipinos, and this number is expected to double in the next 5 years,” Amal shared. “Only 34% are diagnosed, 27% are treated, and only 11% are on insulin. Among those treated, less than 50% are able to manage or control their disease. Globally, 1 life is lost every 7 seconds because of diabetes and its complications.”

Stepping up for World Diabetes Day

Among other factors such as diet and lifestyle, Makhloufi stresses that there is a distinct lack of awareness and understanding on diabetes which has led to its widespread prevalence in recent years. To address this, Sanofi Philippines hosted Healthier/PH sessions: Step Up For World Diabetes Day, a virtual media event which featured a multi-disciplinary panel to tackle the issue of diabetes and educate the public on managing the disease.

“As partners for building a healthier Philippines, we have the chance to step up in solidarity for our friends and family with diabetes. Even a simple gesture of raising awareness, getting the word out to help people better understand the disease and the risk factors behind it can go a long way in the prevention and management of diabetes,” she affirmed.

Other speakers during the online panel include fitness expert, Jinoe Gavan of Takbo.ph, who shared simple at-home workout tips to keep active during quarantine. Social enterprise Gising Gising, represented by Bianca Dualan, RND, was also present during the talk and educated the audience on the proper nutrition and diet for regulating sugar levels, which is essential in managing diabetes.

Lifestyle and Chronic Diseases

“Another way to describe diabetes is a lifestyle disease,” Amal explained. “If we actively promote an active and well-balanced lifestyle for our families, where we get sufficient physical activity and proper nutrition, this will play a major role in reducing the prevalence of chronic disease in the coming years.”

And in its thrust to raise further awareness on the impact of the disease and promote healthier lifestyles, Sanofi Philippines launched the Step Up For World Diabetes Day Virtual Run 2020. This virtual running event was launched on November 14 and runs through December 15, and was initiated in partnership with Takbo.ph.

“I encourage you to step up and take action by joining our first ever Step Up Virtual Run 2020, and inviting others to join as well. Because if we spread awareness one kilometer at a time, one day at a time, one person at time, then together we can make a difference.”

How to Join: 

1. To join, you may register at Takbo.ph, where you can select your preferred distance of 15k, 30k, 50k, or 100k. Registration lasts until November 30 only. 

2. We recommend you use Strava, Nike or Garmin to record and keep track of your time. If you wish to use a treadmill, you may do so provided that your time and distance will be indicated. 

3. Should you choose to run outdoors, always remember to practice social distancing and make use of the proper protective equipment.

For Tiktok Virtual Run Challenge 

1. Register on #StepUp4WDD Virtual Run via https://app.takbo.ph/all-races/step-up-virtual-run-2020 

2. Post a video while running on TikTok and tag 5 of your friends to join.

 3. Use this caption upon posting: I pledge to #StepUp4WDD in the fight against diabetes. I challenge @name1 @name2 @name3 @name4 @name5 to join. 

4. Use the following hashtags upon posting: #WorldDiabetesDay #SanofiPH #PanatangSanofi #DiabetesYourType

For more information on how you can join the Step Up For Diabetes Virtual Run 2020, log on to Takbo.Ph.